Psychoactive cannabinoids

The group of molecules called cannabinoids gets its name from their function of being able to bind or indirectly affect the cannabinoid receptors of the endocannabinoid system. They are among the most important compounds of the cannabis plant.

The main cannabinoids
The development of cannabinoids is very varied. The genetics of a particular species is the determining factor in this. One strain is very rich in THC and the other more in CBD. There are many more of these molecules. Some occur in higher concentration than others. The main cannabinoids will be listed below.

• THC is the main strain. These cannabinoids bind to the CB1 and CB2 receptors of the endocannabinoid system. As most probably know, THC has a major influence on, among other things, the appetite and mood after consumption.
• The second most important cannabinoid in most cannabis strains is CBD. This cannabinoid has the upper hand when it comes to the hemp plant. For most consumers, the use of cannabidiol results in a clear and relaxed effect. It has a low relationship to cannabinoid receptors. In addition, it has an indirect effect on the endocannabinoid system. To this day, the effects of CBD are very promising. This is the reason that it is so popular as a dietary supplement.
CBC often makes up only 0.3% of the total cannabinoid amount. There are only a limited number of selectively bred plants that contain more CBC. CBC activates the CB2 receptors, but shows little activity at the CB1 receptor sites. Research shows that CBC may contribute to healthy brain function.

For example, there are three more important cannabinoids called: CBGA. CBN and THCV. But in order not to make this blog too long, let’s leave it out of consideration for a moment.

The psychoactive cannabinoids
Not all major cannabinoids are psychoactive. In order to induce these effects, the substance must be able to activate the CB1 receptor. This then results in chemical changes in the central nervous system. It stimulates appetite and improves mood. THC, THCV and CBN all create some sort of psychoactive effect.

Finally, the cannabinoids that have no psychoactive effect. These are: CBG and maybe the unexpected CBD. Both substances do not bind to the CB1 receptor. In addition, CBD even appears to slow down the psychoactive effects of THC when consumed together.

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