CBD and COVID-19

The coronavirus has been prevalent all over the world for more than a year now. But what’s the relationship of CBD when it comes to the virus? Figuring out drugs that could be effective with COVID-19 is crucial.

Does CBD have an effect on the virus?
There is no explicit evidence yet that CBD has a curative effect on the virus. Well-founded hypotheses have been made as to why there is a good chance that it will actually have an effect on limiting the severity and progression of the disease.

The hypotheses are:

a. Cannabis sativa extracts with a high amount of cannabidiol can down-regulate the expression of the two major receptors for SARS-CoV2 (Coronavirus 2) in different models of human cover tissue,
b. Cannabidiol exerts a wide range of immunomodulatory and anti-inflammatory effects and can reduce the uncontrolled cytokine production responsible for acute lung injury.
c. It contains PPARγ agonist which means it can show direct antiviral activity.
d. PPARγ agonists are the regulators of fibroblast and myofibroblast activation and can inhibit the development of pulmonary fibrosis, in turn improving lung function in convalescing patients.

All these hypotheses are reasons to further investigate the effect of CBD on the virus and hopefully arrive at a supportive drug against COVID-19.


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